Baseline Clinic Visit

The first clinic visit in a longitudinal study after confirming you are eligible to participate. Usually the baseline visit is a longer visit where a great deal of data is collected. 


Something measurable in the body that can predict the presence or the outcome of a disease.  It can be a specific biological molecule such as a protein or other molecule found in blood or other body fluids. It can be a specific gene.  It can be a unique feature of anatomy. Biomarkers can lead to better understanding of the underlying cause of a disease. And they can help doctors put patients in sub-groups for more targeted treatments or research studies.

Bladder Pain Syndrome (IC/BPS)

Another term to describe the symptoms of Interstitial Cystitis.

Case participant

In scientific research, a case participant is a person who has the disorder being studied. In MAPP, a case participant is someone with the symptoms of a Urologic Chronic Pelvic Pain Syndrome. 

Chronic Fatigue Syndrome

A disorder that causes extreme fatigue.

Chronic Prostatitis (CP/CPPS)

Chronic pelvic pain or discomfort in males. See expanded definition.

Coded data

Data that does not include a participant's personal contact information or anything that could potentially identify the person directly.


A disorder that causes muscle pain and fatigue.

Functional MRI Scan

MRI stands for Magnetic resonance imaging. The MRI machine uses a strong magnet to create clear computerized images of the internal structures of specific parts of the body, including the brain. A special type of MRI called a functional MRI can also tell us which parts of the brain are working at the time of the scan. 


A  unit of DNA that carries the instructions for making a specific protein or set of proteins. Body structures like organs and tissues are made of proteins. Proteins also control chemical reactions in cells, and may carry signals between cells. Genes are found on chromosomes in all living cells.  Genes are the way genetic information is passed from parent to child. 

Healthy Control

In scientific research, a control subject is a person who is used to provide a basis of comparison. For the MAPP study, a healthy control is a person who does not have UCCPS or any other chronic pain condition.

Interstitial Cystitis

See expanded definition.

Irritable Bowel Syndrome

A disorder that affects the large intestine. It can cause abdominal cramping, bloating, and a change in bowel habits. It can cause constipation, diarrhea, or both.

Longitudinal study

A research project that involves studying the same group of individuals over an extended period of time.


The Multidisciplinary Approach to the Study of Chronic Pelvic Pain. Learn more about the MAPP Research Network. 

MAPP Discovery Site

One of multiple sites that recruit study participants and conduct MAPP research studies.

MAPP Data Coordinator Core (DCC)

A site that coordinates MAPP data collection and analysis of data from all Discovery Sites.

Painful Bladder Syndrome

Another term to describe the symptoms of Interstitial Cystitis.

Positive Control

In scientific research, a control subject is a person who is used to provide a basis of comparison. For the MAPP study a positive control is s person who has one of the following chronic pain conditions: fibromyalgia, chronic fatigue syndrome, or irritable bowel syndrome

Pressure Pain Threshold (PPT) test

A pain sensitivity test. It uses special equipment that applies pressure to a participant's thumb. Participants are asked if they felt pressure or pain. If they felt pain, they are asked to rate the level of their pain.

Urologic Chronic Pelvic Pain Syndromes (UCPPS)

A general term use to describe chronic pelvic pain of unknown cause in men and women. In the MAPP study, this includes men and women with Interstitial Cystitis or Bladder Pain Syndrome (IC/BPS) and men with Chronic Prostatitis or Chronic Pelvic Pain Syndrome (CP/CPPS).